Comparison of Survival Outcomes after Laparoscopic Radical Hysterectomy versus Abdominal Radical Hysterectomy in Patients with Cervical Cancer

ObjectiveA meta-analysis was performed to compare survival outcomes including disease-free (DFS) between laparoscopic radical hysterectomy (LRH) and abdominal (ARH) in patients with cervical cancer.Data SourcesWe searched PubMed, EMBASE, Google scholar, the Cochrane library for studies published December 2004 May 2020. Manual searches of related articles relevant bibliographies were also performed.Methods Study SelectionTwo researchers independently extracted data. Studies outcome information included.Tabulation, Integration, ResultsA total 36 eligible clinical trials included this meta-analysis. When all pooled, hazard ratio (HR) LRH risk DFS overall (OS) compared ARH 1.24 (95% confidence interval [CI], 1.09–1.41; p = .001; I2 37.5%) 1.27 CI, 1.04–1.56; .020; 45.5%), respectively. In a subgroup analysis, significant harmful effects increased using HR presented by article (HR, 1.41; 95% 1.21–1.64; <.001), matched retrospective design 1.49; 1.19–1.88; .001), large-scale 1.34; 1.16–1.55; after Laparoscopic Approach Cervical Cancer trial 1.46; 1.25–1.71; <.001). However, did not affect 1.04; 0.59–1.81; .898) or OS 0.57; 0.31–1.05; .073) cancer masses <2 cm.ConclusionThis demonstrated that associated higher recurrence rates than ARH. showed similar among cm (Centre Reviews Dissemination 42020191713).